Exosome Microneedling Hair Restoration

The hair growth cycle typically lasts between 2 to 6 years, depending on the individual. Shedding 50 to 100 hairs per day is normal, but when hair loss exceeds regrowth, it can lead to an imbalance and result in alopecia. COMMON CAUSES OF HAIR LOSS Hair loss is often caused by several factors, the most common being: DHT (Dihydrotestosterone Hormone): High levels of DHT, combined with the genetic sensitivity of hair follicles, can damage and shrink them, preventing healthy hair growth. This eventually leads to alopecia. Although DHT is primarily associated with men, women, especially post-menopausal, can also suffer from DHT-related hair loss due to increasing testosterone levels. Lack of Nutrients: Insufficient intake of essential nutrients weakens the hair bulb, causing thinning hair and a shorter growth cycle. Poor Scalp Microcirculation: Factors such as smoking, stress, and poor lifestyle choices can negatively affect scalp circulation, reducing oxygen and nutrient supply to hair follicles. Genetic Predisposition: A family history of alopecia increases the likelihood of hair loss, making genetics one of the leading causes. Stress: Stress can have a profound impact on overall health and is a common trigger for hair loss. Stress-induced alopecia can be reversed once the stressful situation resolves, but stress can also worsen other forms of alopecia.

Micro-needling is a process called collagen induction therapy (CIT). CIT is the skin’s own ability to repair itself. ​ During this revolutionary procedure, a small, electronic device containing tiny needles is moved over the skin to create thousands of microscopic channels in both the epidermis and upper dermis of the skin. The body responds to this controlled wound healing the same way it would to an injury by releasing powerful growth factors to stimulate not only collagen, but also hair cell growth. ​ Not only that, it also increases blood flow to your scalp, bringing more nutrients to your hair follicles and ultimately leading to healthier and stronger hair. By microneedling your scalp, you're creating the perfect conditions for hair growth. Plus, this treatment makes it easier for topical products to penetrate deep into your scalp where they're needed most. ​ These "micro-channels" allow for deeper penetration of pharmaceutical solutions, resulting in higher efficacy. We use EXOSOMES when microneedling. ​

Protocol: A standard protocol for INNO-EXOMA EXO-SKIN on the scalp involves 3-6 sessions spaced 21 days apart. Individual Variation: The number of sessions needed can vary based on factors like the individual's hair cycle stage, the amount of hair being treated, and the specific type of hair loss. Maintenance: Maintenance treatments can help sustain optimal hair growth. Some patients repeat this cycle every 6-12 months

At Westfield Clinic we use the latest advancements in technology and pharmaceuticals. During the microneedling treatment, we use Exosomes, which are a scientific breakthrough and are already being used in regenerative medicine. Exosomes serve as specialised nanocarriers crucial for cell communication and tissue regeneration. The most significant effects include: Increased ceramide synthesis, leading to skin barrier regeneration. Reduction of inflammation through the downregulation of cytokine levels. Enhanced collagen and elastin synthesis. Increased differentiation of keratinocytes and fibroblasts, activating epidermal cells including hair follicles. Significant regenerative effects that combat the signs of skin aging associated with decreased cell turnover. Hair follicle regeneration by stimulating its activity through cellular interactions. Also contains: Amino Acid Complex, Peptide Complex, Hyaluronic Acid ​ ​

To understand INNO-EXOMA® and its function, we need to delve into the world of exosomes first. Exosomes play a crucial role in extracellular communication and tissue regeneration. They are tiny vesicles released by cells in charge of the exchange of amino acids, proteins, growth factors, anti-inflammatory cytokines, and genetic material between cells. They travel through intercellular spaces to deliver their bioactive cargo to target cells, where it is interpreted as pertinent information that serves as guidelines to enhance cell function and initiate crucial physiological processes. This ultimately leads to outstanding regenerative capabilities that enable tissues to heal themselves. Exosomes possess two exclusive characteristics that elevate them as the most effective nanocarriers: 1. NANO PRECISION Ranging from 30 to 150 nanometers, exosomes stand as the tiniest type of extracellular vesicles, ensuring precise delivery. 2. GUARDIANS OF CARGO Wrapped in a lipid bilayer, exosomes shield their cargo, seamlessly integrating into cells and releasing bioactive substances. EXOSOMES play a vital role in several physiological processes. They promote cell proliferation, migration, and differentiation, ultimately boosting the synthesis of key tissue components, leading to tissue repair and regeneration. They regulate inflammation, promote collagen synthesis, and enhance tissue regeneration

Innoaesthetics’ exosome-like molecule has been created thanks to a cutting-edge bio technology called NARBEX™ (Non-Animal Regenerative Bioengineering Exosome), which allows the assembly of peptide chains in a specific way to replicate the active protein part of a biological exosome. Each vial of INNO-EXOMA® EXO-SKIN contains millions of our exosome-like molecules. Thanks to its intensive regenerative effects, INNO-EXOMA® EXO-SKIN is a versatile product that enhances skin health, targeting the specific needs of each individual. It is beneficial for all skin types and can improve most skin issues. It also contains: 4 Amino Acids for collagen production & tissue repair 3 Amino Acids for antioxidant action 5 Peptides as Biochemical Mediators 2 GAGs for Hyaluronic Acid production Mannitol as Free Radical Scavenger

SAFETY AND ETHICS AT THE CORE. Since cell-derived exosomes contain genetic information, their use is restricted to regenerative medicine for safety reasons. INNOAESTHETICS’ exosome-like molecule is 100% synthetic, not derived from any human, animal, or vegetable cells. It offers high tolerance and poses no health nor allergy risks. INNO-EXOMA® EXO-SKIN is formulated and manufactured in our production plant, complying with the strict European standards and regulations.

No. There may be some very mild discomfort but the treatment is generally very well tolerated. It is not advised to use numbing cream pre-treatment, as numbing cream causes vasoconstriction.

Infection control is taken very seriously at Westfield Clinic. The skin is carefully assessed and prepared. The treatment is performed using single-use sterile needle cartridges in a protected CE-approved microneedling device. Medical Micro-Needling is an option that even those with a fear of needles can consider, as needles are so small and contained within the cartridge that you do not see them.

Not suitable if: Botox or Fillers in the treatment area to be avoided 2 weeks prior.  Pregnant or breastfeeding.  Anti-coagulant therapy – increases potential for bleeding - coagulation status should be checked to confirm normal clotting/bleeding profile.  Haemophiliacs.  History of keloid scarring.  History of radiation therapy within the application area (6 mths post chemo & radiotherapy).  Raised moles or warts.  Skin cancers – melanoma.  Skin infections including any bacterial, viral, fungal, or herpetic infection.  Wounded, sunburned, excessively sensitive skin.  Inflammatory acne within the application area.  Uncontrolled diabetes.  Active eczema, psoriasis or inflamed/severe rosacea in the area.  Oral retinoids (Roaccutane) used within 6 months prior to treatment.  We recommend carrying out a patch test for Fitzpatrick skin types 4 or above.  Unrealistic expectations ​

Following consultation, your skin is cleansed and sanitised, Eosomes are applied, microneedling is performed with a medical-grade needling device. A soothing post-procedure cream and spf is applied.

To minimise bleeding, please avoid taking anti-inflammatory medication, drinking alcohol or taking fish oil supplements for 3 days prior to your treatment. Arrive with freshly washed, clean hair and scalp, totally free of any styling products.

External products after microneedling (such as serums) work best when applied within the first 24 to 48 hours. After that, all the microchannels that you made are closed. When choosing skincare products to apply after microneedling opt for products with a high purity of ingredients, low-irritants and hydrating ingredients (Hyaluronic Acid is recommended)​ ​​ Avoid extended periods in the sun and apply an SPF of 30 or higher when you leave the house - for 7 days. Do not go swimming for at least 48 hours post-treatment. No exercising or strenuous activity for the first 24 hours post-treatment. Sweating and gym environments should be avoided as they can expose you to dirt and bacteria which may cause adverse reactions. It's advisable to avoid washing your hair for at least 4 hours following the treatment. It's also essential to avoid using scalp products with artificial scents for at least a few days post-treatment. You may notice your scalp peeling slightly post-treatment. You might also experience some discomfort or tenderness on your scalp. This is perfectly normal, considering the numerous micro-punctures from the microneedling. Should you notice any persistent inflammation in a specific area, make sure to sanitise the area thoroughly before bedtime. Aloe vera can help calm inflammation. Do not expose your freshly treated scalp to direct sunlight, which can cause unwanted reactions. It's similar to how our skin becomes more susceptible to sunburn while having treatment. Wear a hat or head scarf to help to protect your scalp during this healing time. Please do not engage in intense physical activity, as it can cause the scalp to sweat. In the healing period, the scalp is prone to infection from bacteria and dirt. Lastly, sleeping on a clean pillowcase can also help you prevent potential infections. ​ It's important to remember that there is no one-size-fits-all solution to hair loss. Additional supporting care can also be a helpful factor in the success of microneedling on the scalp, for example, the application of Minoxidil or similar on the scalp. ​

After microneedling, your skin will likely turn a little red/pink which generally lasts a few hours but may be longer. Your skin might also look a little blotchy or be a little swollen. Avoid microneedling if you wish to attend an event within 48 – 72 hours post-treatment. Avoid microneedling if you are feeling unwell or under the weather.

Yes, here are some links to studies on the effectiveness of scalp microneedling... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746236/ https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.14525 https://pubmed.ncbi.nlm.nih.gov/31254437/ and clinical trial of Exosomes:

Thinning hair - Wrinkles - Enlarged Pores - Scarring - incpick acne scars - Loose Skin - Stretch Marks - Hyperpigmentation and Uneven Skin Tone - Uneven Skin Texture - Dull Skin Tone. For other microneedling areas visit our page here.

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The following can be good for hair loss: Minoxidyl to stimulate growth. Nizoral (2% ketokonasole) to block DHT. Caffeine shampoo to stimulate micro circulation. Scalp product containing Aminexil to strengthen hair roots and soften collagen (ie Elvive growth booster or Kerastase Genesis). Supplements - specific. Daily scalp massage/