Microneedling Serums: Compare Fillmed NCTF135HA, Vitaran Polynucleotides, and Exosomes

Microneedling is a popular skincare treatment for improving skin texture, reducing fine lines, and boosting overall skin health. What sets one microneedling session apart from another often depends on the serums or solutions used during the procedure. Three notable options are Fillmed NCTF135HA, Vitaran Polynucleotides, and INNO-EXOMA Exosomes. Understanding their differences can help you choose the best treatment for your skin needs.

What Is Microneedling?

Microneedling is a minimally invasive cosmetic procedure that uses fine, vibrating needles to create thousands of tiny, controlled punctures in the skin's surface. These micro-injuries stimulate the body's natural healing process, encouraging collagen and elastin production. When combined with specialised serums, microneedling will enhance the absorption of active ingredients, making treatments more effective.

The choice of serum plays a crucial role in the results. At Westfield Clinic, we have the option of three:

1) Fillmed NCTF135HA, 2) Vitaran Polynucleotides, and 3) INNO-EXOMA Exosomes. Each offers unique benefits and mechanisms of action.

1) Fillmed NCTF135HA: A Powerful Cocktail for Skin Rejuvenation

Fillmed NCTF135HA is a well-known mesotherapy solution designed to revitalise skin. It contains a blend of hyaluronic acid, vitamins, amino acids, antioxidants, and minerals. This combination supports hydration, cell regeneration, and protection against oxidative stress. We use NCTF135HA in our 'standard' microneedling treatments.

Key Features of Fillmed NCTF135HA

• Hyaluronic Acid: Provides deep hydration and plumps the skin.

• Vitamins and Antioxidants: Help neutralise free radicals that cause premature ageing.

• Amino Acids and Minerals: Support skin cell repair and renewal.

  
  

When used with microneedling, NCTF135HA penetrates deeper layers of the skin, enhancing its rejuvenating effects. It is especially effective for dull, dehydrated skin and early signs of ageing.

2) Vitaran Polynucleotides: Repair and Regeneration from Within

Vitaran Polynucleotides are highly purified, filtered, and sterilised DNA fragments extracted from trout. These molecules promote tissue repair and have anti-inflammatory properties.

What Makes Vitaran Polynucleotides Different?

• Tissue Repair: Polynucleotides stimulate fibroblast activity, which is essential for collagen production.

• Anti-Inflammatory Effects: They reduce redness and irritation, making this serum suitable for sensitive or damaged skin.

• Skin Elasticity: Helps restore firmness and resilience.

  
  

Microneedling with Vitaran Polynucleotides is often recommended for skin that needs healing after damage, such as sun exposure or acne scars. It supports long-term skin regeneration rather than just surface hydration.

3) INNO-EXOMA Exosomes: Cutting-Edge Cell Communication Boost

INNO-EXOMA Exosomes represent a newer approach in skincare. Exosomes are tiny vesicles released by stem cells that carry proteins, lipids, and genetic material. They act as messengers, signalling skin cells to repair and regenerate.

Benefits of INNO-EXOMA Exosomes

• Cell Communication: Exosomes improve the way skin cells interact, accelerating healing.

• Anti-Ageing: They promote collagen synthesis and reduce wrinkles.

• Skin Brightening: Helps even out skin tone, pigmentation, and texture.

  
  

Using INNO-EXOMA Exosomes with microneedling can lead to noticeable improvements in skin quality, especially for mature or photoaged skin. This treatment supports deep cellular renewal beyond what traditional serums offer.

Comparing the Three

Feature	Fillmed NCTF135HA	Vitaran Polynucleotides	INNO-EXOMA Exosomes
Active Ingredients	Hyaluronic acid, 12 vitamins, 24 amino acids, 6 co-enzymes, 6 minerals, 5 nucleosides, antioxidants	Polynucleotides (DNA fragments) 20mg/ml	Stem cell-derived exosomes, high concentration of amino acids, peptides, glycosaminoglycans, and hyaluronic acid
Primary Benefit	Hydration, skin revitalisation, collagen & elastin stimulation and antioxidant protection	Deep, cellular skin regeneration and repair and anti-inflammation. Promotes natural production of collagen and elastin	Enhanced cell communication and regeneration, intensive skin regeneration and rejuvenation, high-intensity collagen/elastin boost, significant anti-ageing
Best For	Dehydrated, dull, early ageing skin, skin quality. Excellent for age 20+ to maintain skin quality and give skin a glow.	Fine lines, crepey skin, acne scars, uneven texture, and damaged or sensitive skin needling rejuvenation. Excellent alternative for those who want the benefits of polynucleotides but prefer to avoid intradermal injections (the standard method of delivery)	Intensive skin rejuvenation, anti-ageing, repair of damaged skin, particularly for those with wrinkles, sagging, acne scars, or hyperpigmentation. It is ideal for all skin types, including sensitive skin, and is effective for treating inflammatory conditions like rosacea
Mechanism	Nourishes and protects skin cells via bio-revitalisation. Antioxidant Protection	Stimulates fibroblasts to increase production of collagen, elastin, and hyaluronic acid. Tissue repair and regeneration. Reduces inflammation.	Exosome nanospheres to mimic intercellular communication, instructing cells to boost collagen, elastin, and hyaluronic acid synthesis. Signals skin cells to repair and renew. Decreases inflammation and pigmentation
Typical Results	Brightness and texture improve around 3 weeks. 8-12 weeks density improves. 3–6 Months collagen production accelerates.	Hydration and fine lines improve within 4 weeks. Optimal results 12-16 weeks after a course	Visible results begin around 1 month after the first session

Choosing the Right Microneedling Serum for You

Selecting between these options depends on your skin concerns and goals:

• If your skin feels dry, tired, or shows early signs of ageing, Fillmed NCTF135HA offers hydration and protection.

• For skin that needs healing from damage or irritation, Vitaran Polynucleotides supports repair and reduces inflammation.

• If you want to target deeper aging signs and improve skin cell function, INNO-EXOMA Exosomes provide advanced regeneration.

What to Expect During Treatment

Microneedling sessions with any of these serums typically last 30 to 60 minutes. After cleansing, a gentle chemical peel is applied, the skin is sanitised, the chosen serum is applied, and the microneedling device gently glides over the skin, creating microscopic channels in the skin. It is very comfortable and often described as a light scratching sensation. A soothing mask is applied during which cooling ice globes gently aid lymphatic drainage, reduce any redness or mild inflammation, before a protective moisturising cream is applied.

Post-treatment, you may experience mild redness or sensitivity for a day or two. Results improve with multiple sessions spaced 4-6 weeks apart.

Summary

The mechanical action of microneedling every 4-6 weeks has numerous benefits, with many clinical studies showing the effectiveness of having ongoing regular treatments - microneedling has now replaced that monthly facial!

Microneedling enhances skin rejuvenation by combining mechanical stimulation with active serums. Fillmed NCTF135HA focuses on hydration and antioxidant support, Vitaran Polynucleotides promotes tissue repair and reduces inflammation, and INNO-EXOMA Exosomes boost cell communication for deep regeneration.

Ultimately, you can rotate, having a course of each, which many of you do, and we see fab results in clinic!